刘忠英

作者: 时间:2021-06-22 点击数:

姓名

刘忠英

职称

教授

办公地点

药学院501

办公电话

13904331190

邮箱

liuzy@jlu.edu.cn

教育背景

1981-1985 本科生,吉林大学化学系

1987-1990 硕士研究生,生物化学, 白求恩医科大学

2001-2005 博士研究生,分析化学,吉林大学化学院

工作经历

2004- 教授 ,博导, 吉林大学药学院

1998-2004 副教授.硕导,吉林大学药学院

1985-1998,讲师, 白求恩医科大学

主讲课程

药物分析学

研究领域

现代药物分析,体内药物分析

科研成果

发表文章:

1.SHI, L., WANG, R., LIU, T., WU, J., ZHANG, H., LIU, Z.* & LIU, S. 2020. A rapid protocol to distinguish between Citri Exocarpium Rubrum and Citri Reticulatae Pericarpium based on the characteristic fingerprint and UHPLC-Q-TOF MS methods. Food Funct, 11, 3719-3729.

2. WANG, Y. & LIU, S.,WANG, R., SHI, L. & LIU, Z.* 2020. Study on the therapeutic material basis and effect of Acanthopanax senticosus (Rupr. et Maxim.) Harms leaves in the treatment of ischemic stroke by PK-PD analysis based on online microdialysis-LC-MS/MS method. Food Funct, 11, 2005-2016.

3. WANG, R., SHI, L., LIU, S., SONG, F., SUN, Z. & LIU, Z.* 2019. Mass spectrometry-based urinary metabolomics for the investigation on the mechanism of action of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. leaves against ischemic stroke in rats. J Ethnopharmacol, 241, 111969.

4. WEI, M., LIU, Y., PI, Z., YUE, K., LI, S., HU, M., SONG, F. & LIU, Z.* 2019a. Investigation of plasma metabolomics and neurotransmitter dysfunction in the process of Alzheimer's disease rat induced by amyloid beta 25-35. Rsc Advances, 9, 18308-18319.

5. WEI, M., LIU, Y., PI, Z., LI, S., HU, M., HE, Y., YUE, K., LIU, T., SONG, F. & LIU, Z.* 2019a. Systematically Characterize the Anti-Alzheimer's Disease Mechanism of Lignans from S. chinensis based on In-Vivo Ingredient Analysis and Target-Network Pharmacology Strategy by UHPLC⁻Q-TOF-MS. Molecules, 24,1203.

6. LIU, Y., WEI, M., YUE, K., WANG, R., MA, Y., MEN, L., PI, Z. & LIU, Z.* 2019. Non-target metabonomic method provided new insights on the therapeutical mechanism of Gancao Fuzi decoction on rheumatoid arthritis rats. J Chromatogr B Analyt Technol Biomed Life Sci, 1105, 93-103.

7. MA, Y., LIU, Z.*, WEI, M. & TSAO, R. 2019. Study on intestinal transport of the glycyrrhizic acid in the Gancaofuzi decoction across the Caco-2 cell monolayer model by HPLC-ESI-MS method. Acta Medica Mediterranea, 35, 3449-3455.

8. LIU, Y., WEI, M., YUE, K., HU, M., LI, S., MEN, L., PI, Z. & LIU, Z.* 2018. Study on Urine Metabolic Profile of Aβ25-35-Induced Alzheimer's Disease Using UHPLC-Q-TOF-MS. Neuroscience, 394, 30-43.

9. JIANG, W., SI, L., LI, P., BAI, B., QU, J., HOU, B., ZOU, H., FAN, X., LIU, Z., LIU, Z.* & GAO, L. 2018. Serum metabonomics study on antidiabetic effects of fenugreek flavonoids in streptozotocin-induced rats. J Chromatogr B Analyt Technol Biomed Life Sci, 1092, 466-472.

10. WEI, M., MA, Y., LIU, Y., ZHOU, Y., MEN, L., YUE, K., PI, Z. & LIU, Z.* 2018. Urinary metabolomics study on the anti-inflammation effects of flavonoids obtained from Glycyrrhiza. J Chromatogr B Analyt Technol Biomed Life Sci, 1086, 1-10.

11. CHEN, W., WU, Y., BI, R., LIU, S., LIU, Z.,* SONG, F. & SHI, Y. 2017. Therapeutic Effects of Selaginella tamariscina on the Model of Acute Gout with Hyperuricemia in Rats Based on Metabolomics Analysis. Chinese Journal of Chemistry, 35, 1117-1124.

12. JIANG, W., GAO, L., LI, P., KAN, H., QU, J., MEN, L. & LIU, Z.* 2017. Metabonomics study of the therapeutic mechanism of fenugreek galactomannan on diabetic hyperglycemia in rats, by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci, 1044-1045, 8-16.

13. MEN, L., PI, Z., ZHOU, Y., WEI, M., LIU, Y., SONG, F. & LIU, Z.* 2017. Urine metabolomics of high-fat diet induced obesity using UHPLC-Q-TOF-MS. J Pharm Biomed Anal, 132, 258-266.

14. MEN, L., PI, Z., ZHOU, Y., LIU, Y., WEI, M., SONG, F. & LIU, Z.* 2017a. Metabolomics insights into diabetes nephropathy and protective effects of Radix Scutellariae on rats using ultra-high performance liquid chromatography coupled with quadrupole time-of- flight mass spectrometry. Rsc Advances, 7, 16494-16504.

15. CHEN, W., WU, Y., ZHAO, X., LIU, S., SONG, F. & LIU, Z.* 2016. Screening the anti-gout traditional herbs from TCM using an in vitro method. Chinese Chemical Letters, 27, 1701-1707.

16. DING, R., JIAN, Y., KAN, H., LIU, Z.,* LIU, S. & ZHOU, J. 2016. Studies on the intestinal absorption of the alkaloids in the Gancaofuzi decoction in a Caco-2 cell culture system by UPLC-MS/MS analysis. Chinese Chemical Letters, 27, 915-919.

17. LIN, H., PI, Z., MEN, L., CHEN, W. & LIU, Z.* 2016b. Urinary metabonomic study of Panax ginseng in deficiency of vital energy rat using ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. J Ethnopharmacol, 184, 10-7.

18. MA, Y., WEI, M., LIU, Y., SONG, F., LIU, Z.*& PI, Z. F. 2016. Study on intestinal transport of Veratrum alkaloids compatible with Panax ginseng across the Caco-2 cell monolayer model by UPLC-ESI-MS method. Chinese Chemical Letters, 27, 215-220.

19. JIAO, A., YU, M., LI, L., JIAO, L. & LIU, Z.* 2019. Determination of cinobufagin and resibufogenin in Bufo Corium by high performance liquid chromatography-mass spectrometry. Chinese Traditional and Herbal Drugs, 50, 3687-3690.

20. WANG, J., JIANG, W., ZHANG, L., WANG, J., ZHAO, X., WANG, Y. & LIU, Z.* 2016. Hypoglycemic effects of saponins, flavonoids, and polysaccharides of fenugreek with different component compatibilities on type 1 diabetic rats. Journal of Jilin Univeristy. Medicine edition, 42, 1081-1086.

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