王毅

作者: 时间:2021-07-02 点击数:

姓名

王毅

职称

教授


办公地点

药学院205室

办公电话


邮箱

wangyi@jlu.edu.cn

教育背景

1989-1993 吉林大学化学系 本科生

1995-1998 白求恩医科大学 硕士研究生

1999-2002 吉林大学 博士研究生

工作经历

1993-1995 白求恩医科大学预防医学院 助教

1998-1999 白求恩医科大学预防医学院 助教/科室秘书

1999-2001 白求恩医科大学药学院 讲师/科室副主任

2001-2004 吉林大学再生医学科学研究所 讲师

2004-2005 吉林大学再生医学科学研究所 副教授/硕导

2006-2008 吉林大学药学院 副教授/硕导

2008- 吉林大学药学院 教授/硕导

2009- 吉林大学药学院 教授/博导

主讲课程

再生医学,医学伦理学,组织工程学

研究领域

肿瘤疫苗,肿瘤生物治疗,肿瘤干细胞

科研成果

Pulication:

1. Fu C, Wang L, Tian G, Zhang C, Zhao Y, Xu H, Su M, Wang Y*. Enhanced anticancer effect of oncostatin M combined with salinomycin in CD133+ HepG2 liver cancer cells. Oncol Lett. 2019 Feb;17(2):1798-1806.

2. Fu C, Zhou N, Zhao Y, Duan J, Xu H, Wang Y*. Dendritic cells loaded with CD44+ CT-26 colon cell lysate evoke potent antitumor immune responses. Oncol Lett. 2019 Dec;18(6):5897-5904.

3. Zhang C, Chen W, Zhang X, Zheng Y, Yu F, Liu Y, Wang Y*. Grape seed proanthocyanidins induce mitochondrial pathway-mediated apoptosis in human colorectal carcinoma cells. Oncol Lett. 2017 Nov;14(5):5853-5860.

4. Zhihua Cheng, Zhenshengnan Li, Ke Ma, Xiaoyu Li, Nan Tian, Jinyue Duan, Xu Xiao, and Yi Wang*. Long Non-coding RNA XIST Promotes Glioma Tumorigenicity and Angiogenesis by Acting as a Molecular Sponge of miR-429. J Cancer. 2017; 8(19): 4106–4116.

5. Zhang C, Gong P, Liu P, Zhou N, Zhou Y, Wang Y*. Thioridazine elicits potent antitumor effects in colorectal cancer stem cells. Oncol Rep. 2017;Feb 37(2):1168-1174

6. Teng saying, Wang Yi, Li Pingya, Liu Jinhua, Wei Anhui, Wang Haotian, Meng Siangkun, Pan Di and Zhang Xinmin*. Effects of R type and S type ginsenoside Rg3 on DNA methylation in human hepatocarcinoma cells. Molecular Medicine Reports, 2017 Apr;15(4):2029-2038

7. Zhang C, Miyatake H, Wang Y, Inaba T, Wang Y, Zhang P, Ito Y*. A Bioorthogonal Approach for the Preparation of a Titanium-Binding Insulin-like Growth-Factor-1 Derivative by Using Tyrosinase. Angew Chem Int Ed Engl. 2016 Sep 12;55(38):11447-51.

8. Zhang C, Tian Y, Song F, Fu C, Han B, Wang Y*. Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells. Oncol Rep. 2015 Nov;34(5):2469-76.

9. Xiaoyue Zhou, Shin-Hye Park, Hongli Mao, Takashi Isoshima, Yi Wang, and Yoshihiro Ito. Nanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement. Int J Nanomedicine. 2015 Sep 2;10:5597-607.

10. Na Li, Yan Zhao,* Yi Wang,* Yan Lu, Yuehong Song, Zhifang Huang, Yawen Li, and Jingzhe Zhao* . Aqueous Synthesis and Visible-Light Photochromism of Metastable h-WO3 Hierarchical Nanostructures. Eur. J. Inorg. Chem. 2015, 2804–2812

11. Yue Zhou, Hongli Mao, Binata Joddar, Nobuhisa Umeki, Yasushi Sako, KenIchi Wada, Chieko Nishioka, Eiki Takahashi, Yi Wang & Yoshihiro Ito*. The significance of membrane fluidity of feeder cell-derived substrates for maintenance of iPS cell stemness. Scientific Reports 2015 Jun 12;5:11386

12. Changhao Fu, Zi Yan, Hao Xu, Chen Zhang, Qi Zhang, Anhui Wei, Xi Yang and Yi Wang*. Isolation, identification and differentiation of human embryonic cartilage stem cells. Cell Biology International. Cell Biol Int. 2015 Jul;39(7):777-87.

13. Wenji Sun#, Yi Wang#; James E East; Amy Kimball; Katherine Tkaczuk; Susan Kesmodel; Scott E Strome; Tonya J. Webba*Invariant natural killer T cells generated from human adult hematopoietic stem-progenitor cells are poly-functional. Cytokine 2015;72(1):48-57 (#: co-first author)

14. Fuqiang Zhang, Feng Hao, Dong An, Linlin Zeng, Yi Wang, Xuemin Xu, and Mei-Zhen Cui*. Matricellular Protein Cyr61 Is a Key Mediator of Platelet-derived Growth Factor-induced Cell Migration. J Biol Chem. 2015 Mar 27;290(13):8232-42.

15. Pengfei Liu#, Yetong Feng#, Yi Wang1*, Yulai Zhou1*. Therapeutic action of bone marrow-derived stem cells against acute kidney injury. Life Sciences. 2014 Oct 12;115(1-2):1-7.

16. Pengfei Liu, Yetong Feng, Chao Dong, Dandan Yang2, Bo Li, Xin Chen, Zhongjun Zhang, Yi Wang*, Yulai Zhou*, Lei Zhao*Administration of BMSCs with Muscone in Rats with Gentamicin-Induced AKI Improves Their Therapeutic Efficacy . PLoS ONE 2014; 9(5): e97123.

17. Cong Zhong-Yi, Lin Shuang-Shen, Cong Deng-Li, Su Xiao-Yun, Wang Yi, Zhou Yu-Lai. Effect of Ginsenoside Rh3 on Proliferation and Apoptosis of Human Colon Carcinoma Cells. Chinese Journal of Gerontology, 2010; 30(18):2644-6

18. Bo Han, Yiwen Jiang, Chen Zhan, Yue Zhou, Yi Wang*. The Effect of 20( S ) - Ginsenoside Rg3 on the Proliferation and Apoptosis of colon cancer stem cells in vitro. 2012; 32(20): 4431-3

19. Li Linzhi,Zhao Jingzhe, Wang Yi*, Li Yunling, Ma Dechong, Zhao Yan, Hou Shengnan, Hao Xinli. Oxalic acid mediated synthesis of WO3•H2O nanoplates and self-assembled nanoflowers under mild condition. J. Solid State Chem.2011; 184(7);1661-5

20. Lianzhe Hu , Jie Gao , Yi Wang* and Guobao Xu*. Electrochemiluminescence of tris(2,2-bipyridyl)ruthenium(II) in the presence of hydrazine and its derivatives. Analytical Methods. 2011, 3, 1786-1789

21. Xu YY, Chen Y, Wang Y*. Progress in cancer stem cell research, Chinese Journal of Gerontology, 2009;29(11):2823-5

22. YANG Fan,ZHOU Yulai , WANG Yi , et al . The animal experimental study on Iodine-125 Interstitial Brachytherapy in Pulmonary Carcinoma cell ( A549) Chin J Lab Diagn, 2008 ,12(12):1485-7

23. WANG Yi, WANG Fang, ZHAO Hong-Yu, et al. Prostatic acid phosphatase: new immunotherapeutic target of colon adenocarc inoma. Chinese Journal of Gerontology, 2008;28(18):1804-7

24. SU Xiao-yun, WANG Yi, WANG Fang, et al. Scr eening and Gene Sequencing of Recombinant Human Anti-HBs Antibody. Chin J Biologicals. 2008;21(9):749-51

25. CAI Zibin, WANG Yi, LI Wei, et al. Experimental Research on the anti-cancer effect induced by DC loaded with tumor antigen in vitro. Chinese Journal of Gerontology.2008;28(17):1691-3

26. SU Xiao-yun, WANG Yi, WANG Fang, et al. Expression of Recombinant Human Anti-HBs Antibody. Chinese Journal of Gerontology, 2008, 28(16):1611-1612.

27. SU Xiao-yun, WANG Yi, WANG Fang, et al. Screening and Gene Sequencing of Recombinant Human Anti-HBs Antibody. Chin J Biologicals, 2008, 21(9):749-751.

28. WANG Yi, SU Xiao-yun, SHI Yi, et al. In Vitro Induction of Colon Cancer -specific CTLs with Prostate-specific Antigen. Chin J Biologicals, 2008, 21(8):665-8.

29. WANG Fang, WANG Yi, SU Xiao-yun, et al.Experimental study of HER2 /neu chiral polypeptide vaccine of breast cancer. Chinese Journal of Gerontology, 2008, 28(14):1367-9.

30. WANG Yi, Wang Fang, Su Xiao-yun, et al. Expression of prostatic acid phosphatase in non-prostate adenocarcinomas. J Fourth Mil Med Univ.2007,28(19):1775-7.

31. Takao Y, Yamada A, Yutani S, Takedatsu H, Ono T, Etoh K, Wang Y, Suzuki S, Ide T, Shimotohno K, Sata M, Itoh K. Identification of new immunogenic peptides in conserved regions of hepatitis C virus (HCV) 1b with the potentiality to generate cytotoxic T lymphocytes in HCV1b(+) HLA-A24(+) patients. Hepatol Res. 2007;37(3):186-95.

32. WANG Yi, Takao Y, Harada M, et al. New epitope peptides derived from Hepatitis C virus (HCV) 2a which have the capacity to induce cytotoxic T lymphocytes in HLA-A2+ HCV-infected patients. Microbiol Immunol. 2006;50(11):857-65.

33. WANG Yi, Takao Y, Harada M, et al. Identification of hepatitis C virus (HCV) 2a-derived epitope peptides having the capacity to induce cytotoxic T lymphocytes in human leukocyte antigen-A24(+) and HCV2a-infected patients. Cell Immunol. 2006;241(1):38-46.

34. WANG Yi, Harada M, Yano H, et al. Prostate-specific antigen-reactive cytotoxic T lymphocyte precursors in colon cancer patients. Oncology Report. 2006;15 (2):317-321.

35. WANG Yi, Harada M, Yano H, et al. Prostatic acid phosphatase as a target molecule in specific immunotherapy for patients with non-prostate adenocarcinoma. Journal of Immunotherapy , 2005;28(6):535-541

36. WANG Yi, Harada M, Yamada A , Itoh K. Expression of prostatic acid phosphatase in a variety of tumor types. Cancer Science, 2004;95: Supplement 294.

37. WANG Yi, SU Xiao-Yun, et al. Induction of specific CTLs in BALB/c mice by chiral MUC1 synthetic peptide Vaccine. J Fourth Mil Med Univ ,2004; 25 (16): 1452-1455.

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